REJURAN

Polynucleotide Skin Healer

Rejuran is a type of injectable skin boosting treatment used in aesthetic medicine to improve skin texture, hydration, and overall appearance.
Rejuran is made of Polynucleotides (PN), a DNA fragment derived from salmon. These PN molecules are known for their regenerative properties, helping to repair damaged skin and stimulate collagen production.

Main Benefits Include:

  • Skin healing, cell repair and skin regeneration.

  • By stimulating collagen production, it helps improve the skin's elasticity & firmness

  • It boosts moisture retention in the skin, leading to a more hydrated appearance.

  • Anti-aging effects by reducing the appearance of fine lines and wrinkles.

  • Reduction in acne scars and pigmentation, evening out skin tone and texture.

  • It is often used on the face, neck, and hands to rejuvenate the skin, giving a smoother, more youthful look.



Rejuran treatment is typically administered in multiple sessions to achieve optimal results.

The general recommendation is as follows:

  • Initial treatment phase: 3 to 4 sessions, spaced about 2-3 weeks apart. This allows enough time for the skin to respond and start the regeneration process.

  • Maintenance phase: After completing the initial phase, maintenance treatments are recommended every 4 to 6 months to sustain the benefits and prolong the skin's rejuvenation.


However, the frequency can vary depending on individual skin conditions, age, and desired outcomes. Patients with more severe skin concerns, like deeper wrinkles or acne scarring, may need additional sessions or more frequent treatments initially.

Want More Info? Review the clinical studies in the links below.

A survey on the cosmetic use of injectable polynucleotide: The pattern of practice among Korean Dermatologists

Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double-blind, split-face trial

Treatments of Infra-Orbital Dark Circles by Various Etiologies